In vivo and in vitro phosphorylation of DNA-dependent RNA polymerase of Escherichia coli by bacteriophage-T7-induced protein kinase.
Proc Natl Acad Sci U S A
; 72(7): 2506-10, 1975 Jul.
Article
de En
| MEDLINE
| ID: mdl-1101258
ABSTRACT
After infection with bacteriophage T7 the beta' and to a lesser extent the beta subunits of E. coli DNA-dependent RNA polymerase (nucleosidetriphosphateRNA nucleotidyltransferase, EC 2.7.7.6) are phosphorylated by a phage-gene-encoded protein kinase (ATPprotein phosphotransferase, EC 2.7.1.37). The phosphorylation occurs on threonine residues and appears site-specific. It is probably the molecular basis of the early transcriptional control.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Protein kinases
/
DNA-directed RNA polymerases
/
Coliphages
/
Escherichia coli
Langue:
En
Journal:
Proc Natl Acad Sci U S A
Année:
1975
Type de document:
Article