Structure of a D-glycero -D-manno-heptan from the lipopolysaccharide of Helicobacter pylori.
Carbohydr Res
; 331(2): 219-24, 2001 Mar 22.
Article
de En
| MEDLINE
| ID: mdl-11322737
ABSTRACT
A lipopolysaccharide (LPS) was isolated by hot phenol-water extraction from Helicobacter pylori strain D4 and found to contain no fucosylated poly-N-acetyllactosamine chain typical of most H. pylori strains studied but a homopolymer of D-glycero-D-manno-heptose (DD-Hep). The heptan attached to a core oligosaccharide was released by mild acid degradation of the LPS, and the following structure of the trisaccharide-repeating unit was established by chemical methods and 1H and 13C NMR spectroscopy --> 2)-D-alpha-D-Hepp-(1 --> 3)-D-alpha-D-Hepp-(1 --> 3)-D-alpha-D-Hepp-(1 -->. 1H NMR spectroscopy performed on small amounts of the intact LPS revealed the presence of the same polysaccharide in LPS of H. pylori strains D2 and D5, but not strain D10.
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Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Lipopolysaccharides
/
Helicobacter pylori
/
Heptose
Langue:
En
Journal:
Carbohydr Res
Année:
2001
Type de document:
Article
Pays d'affiliation:
Suède