Nasal provocation testing: a review.
Ann Allergy Asthma Immunol
; 86(4): 355-64; quiz 364-5, 386, 2001 Apr.
Article
de En
| MEDLINE
| ID: mdl-11345277
ABSTRACT
OBJECTIVE:
This review focuses on the uses of nasal provocation testing (NPT) for scientific investigations of the mechanisms of allergic and nonallergic rhinitis. It also describes the use of NPT as a diagnostic tool in clinical practice. The indications, contraindications, advantages, and limitations of different techniques for evaluation of nasal responses are reviewed. The paper familiarizes investigators with particulars of different nasal delivery systems, provocation agents, nasal patency measurements, secretion collection, and nasal lavage techniques. DATA SOURCES Relevant publications obtained from a literature review. STUDY SELECTION Relevant publications on the topics of NPT, allergic, and nonallergic rhinitis were critically evaluated. RESULTS ANDCONCLUSIONS:
To date, NPT has been used primarily as a research tool for the investigation of allergic and nonallergic rhinitis with a wide variety of techniques depending on the specific scientific purposes. NPT will continue to provide useful information about the pathogenesis of airway diseases. Standardized nasal provocation testing has the potential to become a more frequently used clinical test in the diagnosis of allergic and occupational rhinitis and for determination of the appropriate and focused therapy.
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Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Rhinite
/
Tests de provocation nasale
Type d'étude:
Etiology_studies
/
Prognostic_studies
Limites:
Humans
Langue:
En
Journal:
Ann Allergy Asthma Immunol
Sujet du journal:
ALERGIA E IMUNOLOGIA
Année:
2001
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique