Transfection-enforced Bcl-2 overexpression and an anti-Parkinson drug, rasagiline, prevent nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase induced by an endogenous dopaminergic neurotoxin, N-methyl(R)salsolinol.

Maruyama, W; Akao, Y; Youdim, M B; Davis, B A; Naoi, M

Maruyama, W; Akao, Y; Youdim, M B; Davis, B A; Naoi, M.

Affiliation

Maruyama W; Laboratory of Biochemistry and Metabolism, Department of Basic Gerontology, National Institute for Longevity Sciences, Obu, Aichi, Japan.

J Neurochem ; 78(4): 727-35, 2001 Aug.

Article de En | MEDLINE | ID: mdl-11520893

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Collection: 01-internacional Base de données: MEDLINE Sujet principal: Salsolines / Noyau de la cellule / Apoptose / Protéines proto-oncogènes c-bcl-2 / Transport nucléaire actif / Tétrahydroisoquinoléines / Glyceraldehyde 3-phosphate dehydrogenases / Indanes Limites: Animals / Humans Langue: En Journal: J Neurochem Année: 2001 Type de document: Article Pays d'affiliation: Japon Pays de publication: Royaume-Uni

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