A randomized controlled trial of azithromycin versus doxycycline/ciprofloxacin for the syndromic management of sexually transmitted infections in a resource-poor setting.
J Antimicrob Chemother
; 49(5): 875-8, 2002 May.
Article
de En
| MEDLINE
| ID: mdl-12003988
ABSTRACT
A randomized controlled trial was carried out to assess the effectiveness of azithromycin versus a standard regimen with doxycycline/ciprofloxacin in the treatment of sexually transmitted infections in a resource-poor environment. Infection with Chlamydia trachomatis was cured in 23/24 (95.8%) of women in the azithromycin arm versus 19/21 (90.5%) in the doxycycline arm (P = 0.6), resulting in three treatment failures. Gonorrhoea was cured in 55/56 (98.2%) women, with one treatment failure in a patient with concomitant C. trachomatis infection. These results indicate that a single oral dose of azithromycin may prove to be a more effective and convenient treatment for sexually transmitted infections in women in a resource-poor environment
Recherche sur Google
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Maladies sexuellement transmissibles bactériennes
/
Ciprofloxacine
/
Doxycycline
/
Azithromycine
/
Antibactériens
Type d'étude:
Clinical_trials
/
Observational_studies
/
Prognostic_studies
Limites:
Female
/
Humans
Pays/Région comme sujet:
Africa
Langue:
En
Journal:
J Antimicrob Chemother
Année:
2002
Type de document:
Article
Pays d'affiliation:
République d'Afrique du Sud