HLA in Egyptian children with biliary atresia.
J Pediatr
; 141(3): 432-3, 2002 Sep.
Article
de En
| MEDLINE
| ID: mdl-12219069
ABSTRACT
We studied the human leukocytes antigens in 18 Egyptian children with biliary atresia (BA) without extrahepatic congenital malformations. There was a significant increased frequency of both B8 and DR3 (83.3% and 94.4% in patients with BA compared with 6.5% and 14.9% in the general population, respectively). Ten patients had the B8/DR3 haplotype. Our results support the hypothesis that genetic factors may play a role in susceptibility to BA.
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Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Atrésie des voies biliaires
/
Antigènes HLA
Type d'étude:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limites:
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Pays/Région comme sujet:
Africa
Langue:
En
Journal:
J Pediatr
Année:
2002
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique