The influence of cardiac diastole on weaning from mechanical ventilation.

ABSTRACT

Hemodynamic changes occur during weaning from mechanical ventilation, especially after disconnection from positive pressure ventilation. Their importance has been insufficiently studied, although some refer to their role in weaning. The authors studied the hemodynamic implications after ventilator disconnection, using echocardiography. They found isovolumetric relaxation time to be a good predictor of successful weaning, proving the importance of the diastole changes with the hemodynamic adaptation in the transition to negative pressure ventilation.