[Detection of serum Lp(a) level of coronary heart disease and its clinical significance].

ABSTRACT

OBJECTIVE: To study the association of human serum Lp(a) level and coronary heart diseases. METHODS: Objects examined were conposed of 2 groups CHD (39 cases) and healthy controls (52 cases). Lp (a), TC, HDL-C, TG, apoB of two groups were determined and the results were done with statistic analysis. RESULTS: The mean serum Lp(a) concentrations (mg.L-1) in coronary heart disease group were shown higher significantly than that in the control group (P < 0.01). However, there were no significant correlation between the mean serum Lp(a) and the mean serum TC, HDL-C, TG, spoAI and aopB.(P > 0.05). CONCLUSIONS: Serum Lp(a) level is closely related to the occurrence of coronary heart disease. Lp(a) is a single risk factor for coronary heart disease. Detecting the determination of serum Lp(a) is extremely valuable to the clinical prediction and diagnosis of CHD.