[Pulse blood pressure (according to 24-hour monitoring) and left ventricular myocardial structural changes in patients with hypertensive disease]. / Pul'sovoe arterial'noe davlenie (po dannym sutochnogo monitorirovaniia) i strukturnye izmeneniia miokarda levogo zheludochka u bol'nykh gipertonicheskoi bolezn'iu.
Ter Arkh
; 74(12): 21-4, 2002.
Article
de Ru
| MEDLINE
| ID: mdl-12577833
ABSTRACT
AIM:
To study a relationship of the magnitude of structural changes in the left ventricle (LV) to the mean daily pulse blood pressure (PBP) in patients with hypertensive disease (HD). MATERIALS ANDMETHODS:
70 male patients (mean age 49 +/- 1 years) with stages I (n = 54) to 11 (n = 16) HD. LV mass (LVM) was estimated by echocardiography according to the formula derived by R. B. Devereux et al. and normalized to body surface area [the LVM index (LVMI)]. The relative thickness index (RTI) for the posterior wall (PWRTI) and ventricular septum (VSRTI) was calculated as a ratio of the sum of PWRTI and VSRTI to the LV end-diastolic size. LVMI > 125 g/m2 was considered to be a criterion for LV hypertrophy (LVH). 24-hour blood pressure (BP) monitoring was performed with a Spacelabs-90207 device (USA). According to the 24-hour PBP value, the patients were divided into 2 groups 1) those (n = 17) having PBP24 > 53 mm HG and 2) those (n = 53) having PBP24 < 53 mm Hg.RESULTS:
Group 1 patients were found to have significantly higher LVMI, LV WRTI, and incidence of LVH and a complex of changes in the BP profile as higher values of 24-hour systolic, diastolic and mean BP, PBP, and BP variations. Multiple regression analysis revealed a highly significant contribution of PBP24 to the development of LVH.CONCLUSION:
The pedictive value of PBP as an index that characterizes a dynamic pressure load in regard to LV structural changes is higher than that of mean BP as a static load index and a BP variation index.
Recherche sur Google
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Pouls
/
Pression sanguine
/
Hypertrophie ventriculaire gauche
/
Hypertension artérielle
Limites:
Humans
/
Male
/
Middle aged
Langue:
Ru
Journal:
Ter Arkh
Année:
2002
Type de document:
Article