[Neuropsychological changes and bilateral subthalamic deep brain stimulation in Parkinson's disease]. / Efectos cognitivos de la estimulación cerebral profunda sobre el núcleo subtalámico en la enfermedad de Parkinson.
Neurologia
; 18(3): 139-45, 2003 Apr.
Article
de Es
| MEDLINE
| ID: mdl-12677479
ABSTRACT
INTRODUCTION:
To investigate neuropsychiatric changes in Parkinson's disease (PD) patients after 12 months of bilateral subthalamic deep brain stimulation (DBS-STN).SUBJECTS:
Nine out of 23 patients with PD subjected to DBS-STN were included. The mean follow-up of this cohort was 12 months, mean disease duration 14.2 5.5 years and mean UPDRS motor score in <METHODS:
Patients were selected on the basis of CAPSIT criteria. They underwent bilateral implant of stimulators in STN under stereotactic conditions. Quality of life scale (PDQ 39), depression scale (Brev-Cet), frontal function test (Stroop, Wisconsin, verbal fluency) and memory evaluation (Barcelona test) were monitored at baseline in <RESULTS:
The patients' motor scores improved on an average of 40.2 % (p = 0.0002) in <CONCLUSION:
DBS-STN in PD patients seems to be an effective tool for improving their quality of life, due to its benefits on motor function, verbal memory and mood. Bilateral DBS-STN did not affect either verbal fluency or executive functions in our patients. Neuropsychological assessment is a good tool for selection and study of the operated patients.
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Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Maladie de Parkinson
/
Électrothérapie
/
Noyau subthalamique
Type d'étude:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Aspects:
Patient_preference
Limites:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Langue:
Es
Journal:
Neurologia
Sujet du journal:
NEUROLOGIA
Année:
2003
Type de document:
Article
Pays d'affiliation:
Espagne