The effect of combined thrombolysis with rtPA and tirofiban on ischemic brain lesions.
Neurology
; 62(11): 2110-2, 2004 Jun 08.
Article
de En
| MEDLINE
| ID: mdl-15184627
ABSTRACT
To determine the effect of systemic thrombolysis with low-dose recombinant tissue plasminogen activator (rtPA) and the body-weight adjusted platelet GPIIb/IIIa receptor antagonist tirofiban, the authors performed lesion volumetry on magnetic resonance perfusion and diffusion images recorded before thrombolysis and on T2-weighted magnetic resonance images on day 8. Treatment with rtPA and tirofiban (n = 13) resulted in a 50% lesion reduction (p < 0.03), while lesion reduction was less in rtPA treatment (n = 16) and absent in nontreated patients (n = 18).
Recherche sur Google
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Tyrosine
/
Traitement thrombolytique
/
Encéphalopathie ischémique
/
Activateur tissulaire du plasminogène
/
Infarctus du territoire de l'artère cérébrale moyenne
Type d'étude:
Clinical_trials
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limites:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Langue:
En
Journal:
Neurology
Année:
2004
Type de document:
Article
Pays d'affiliation:
Allemagne