Human sympathetic activation by alpha2-adrenergic blockade with yohimbine: Bimodal, epistatic influence of cytochrome P450-mediated drug metabolism.

Le Corre, Pascal; Parmer, Robert J; Kailasam, Mala T; Kennedy, Brian P; Skaar, Todd P; Ho, Herbert; Leverge, Roger; Smith, Douglas W; Ziegler, Michael G; Insel, Paul A; Schork, Nicholas J; Flockhart, David A; O'connor, Daniel T

Le Corre, Pascal; Parmer, Robert J; Kailasam, Mala T; Kennedy, Brian P; Skaar, Todd P; Ho, Herbert; Leverge, Roger; Smith, Douglas W; Ziegler, Michael G; Insel, Paul A; Schork, Nicholas J; Flockhart, David A; O'connor, Daniel T.

Affiliation

Le Corre P; Laboratoire de Pharmacie Galenique et Biopharmacie, Universite de Rennes I, Rennes, France.

Clin Pharmacol Ther ; 76(2): 139-53, 2004 Aug.

Article de En | MEDLINE | ID: mdl-15289791

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Collection: 01-internacional Base de données: MEDLINE Sujet principal: Polymorphisme génétique / Yohimbine / Ethnies / Récepteurs alpha-2 adrénergiques / Antagonistes alpha-adrénergiques / Cytochrome P-450 enzyme system Type d'étude: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limites: Female / Humans / Male Langue: En Journal: Clin Pharmacol Ther Année: 2004 Type de document: Article Pays d'affiliation: France

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