Arc and resistance welding and tumours of the endocrine glands: a Swedish case-control study with focus on extremely low frequency magnetic fields.
Occup Environ Med
; 62(5): 304-8, 2005 May.
Article
de En
| MEDLINE
| ID: mdl-15837851
ABSTRACT
BACKGROUND:
Mechanisms for potential effects of extremely low frequency (ELF) magnetic fields on carcinogenesis have not been identified. A potential pathway could be an interaction with the endocrine system.AIMS:
To analyse occupational exposure to ELF magnetic fields from welding, and tumours of the endocrine glands.METHODS:
This case-control study was based on a cohort with an increased prevalence of high exposed individuals. A total of 174 incident cases of tumours of the endocrine glands, 1985-94, were identified and data were obtained from 140 (80%) of these cases; 1692 controls frequency matched on sex and age were selected, and information on 1306 (77%) individuals was obtained. A short questionnaire was sent to a work administrator at the workplaces of the cases and controls. The exposure assessment was based on questions about job tasks, exposure to different types of welding, and exposure to solvents.RESULTS:
There was an overall increased risk for all tumours of the endocrine glands for individuals who had been welding sometime during the follow up. The increased risk was attributable to arc welding; for resistance welding there was no clear evidence of an association. We found an increased risk for the adrenal glands in relation to arc welding, and for the parathyroid glands in relation to both arc welding and resistance welding. An imprecise increase in risk was also noted for tumours of the pituitary gland for arc welding. No confounding effect was found for solvent exposure, and there was no sign of biological interaction.CONCLUSION:
The increased risks of endocrine gland tumours related to welding might be explained by exposure to high levels of ELF magnetic fields.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Soudage
/
Exposition professionnelle
/
Tumeurs des glandes endocrines
/
Magnétisme
/
Maladies professionnelles
Type d'étude:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limites:
Female
/
Humans
/
Male
Pays/Région comme sujet:
Europa
Langue:
En
Journal:
Occup Environ Med
Sujet du journal:
MEDICINA OCUPACIONAL
/
SAUDE AMBIENTAL
Année:
2005
Type de document:
Article
Pays d'affiliation:
Suède