Ubiquitin and ubiquitin-like proteins as multifunctional signals.
Nat Rev Mol Cell Biol
; 6(8): 599-609, 2005 Aug.
Article
de En
| MEDLINE
| ID: mdl-16064136
ABSTRACT
Protein ubiquitylation is a recognized signal for protein degradation. However, it is increasingly realized that ubiquitin conjugation to proteins can be used for many other purposes. Furthermore, there are many ubiquitin-like proteins that control the activities of proteins. The central structural element of these post-translational modifications is the ubiquitin superfold. A common ancestor based on this superfold has evolved to give various proteins that are involved in diverse activities in the cell.
Recherche sur Google
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Ubiquitines
/
Transduction du signal
/
Maturation post-traductionnelle des protéines
/
Ubiquitine
/
Proteasome endopeptidase complex
Limites:
Animals
/
Humans
Langue:
En
Journal:
Nat Rev Mol Cell Biol
Sujet du journal:
BIOLOGIA MOLECULAR
Année:
2005
Type de document:
Article
Pays d'affiliation:
Royaume-Uni