Pulmonary hypertension and right-sided heart failure in an adult llama with hepatic disease.
J Am Vet Med Assoc
; 228(5): 756-9, 2006 Mar 01.
Article
de En
| MEDLINE
| ID: mdl-16506943
ABSTRACT
CASE DESCRIPTION A 13-year-old llama was examined because of lethargy, inappetence, and syncope. CLINICAL FINDINGS:
Physical examination revealed muffled heart and lung sounds and peripheral edema. Clinicopathologic abnormalities included lymphopenia, hyperglycemia, prerenal azotemia, mild hyponatremia, mild hypoalbuminemia, and high gamma-glutamyltransferase and creatine kinase activities. On ultrasonography, the liver appeared hyperechoic and ascites and pleural effusion were seen. Echocardiography revealed severe dilatation of the right atrium, right ventricle, and pulmonary artery; severe tricuspid regurgitation; and high right ventricular systolic pressure consistent with right-sided heart failure secondary to pulmonary hypertension. TREATMENT ANDOUTCOME:
Treatment with furosemide was attempted, but because of failing health, the llama was euthanized 4 weeks later. Macronodular cirrhosis of the liver, glomerulonephritis, and intimal fibrosis and medial hypertrophy of muscular pulmonary arteries were seen on histologic examination of postmortem specimens. CLINICAL RELEVANCE Findings in this case were similar to those reported for human patients with portopulmonary hypertension secondary to hepatic cirrhosis. Pulmonary hypertension secondary to hepatic disease should be considered in the differential diagnosis of right-sided heart failure.
Recherche sur Google
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Camélidés du Nouveau Monde
/
Défaillance cardiaque
/
Hypertension pulmonaire
/
Maladies du foie
Type d'étude:
Diagnostic_studies
/
Etiology_studies
Limites:
Animals
Langue:
En
Journal:
J Am Vet Med Assoc
Année:
2006
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique