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The fate of the distal aorta after repair of acute type A aortic dissection.
Halstead, James C; Meier, Matthias; Etz, Christian; Spielvogel, David; Bodian, Carol; Wurm, Michael; Shahani, Rohit; Griepp, Randall B.
Affiliation
  • Halstead JC; Department of Cardiothoracic Surgery, Mount Sinai School of Medicine, New York, NY 10029, USA. jameschalstead@yahoo.co.uk
J Thorac Cardiovasc Surg ; 133(1): 127-35, 2007 Jan.
Article de En | MEDLINE | ID: mdl-17198797
ABSTRACT

OBJECTIVES:

The residual aorta's behavior after repair of acute type A dissection is incompletely understood. We analyzed segmental growth rates, distal reoperation, and factors influencing long-term survival.

METHODS:

One hundred seventy-nine consecutive patients (70% male; mean age, 60 years) with acute type A dissection underwent aggressive resection of the intimal tear and open distal anastomosis (1986-2003). Hospital mortality was 13.4%. Survivors had serial computed tomographic scans digitization yielded distal segmental dimensions. Segment-specific average rates of enlargement and factors influencing faster growth were analyzed. Distal reoperations and patient survival were examined.

RESULTS:

Eighty-nine (57%) patients had imaging data sufficient for growth rate calculations. The median diameters after repair were as follows aortic arch, 3.6 cm; descending aorta, 3.7 cm; and abdominal aorta, 3.2 cm. Subsequent growth rates were 0.8, 1.0, and 0.8 mm/y, respectively. Initial size of greater than 4 cm (P = .005) and initial diameter of less than 4 cm with a patent false lumen (P = .004) predicted greater growth in the descending aorta, and male sex (P = .05) significantly affected growth in the abdominal aorta. No significant factors were found for the aortic arch. There were 25 distal aortic reoperations (16 patients), and risk of reoperation was 16% at 10 years. Risk factors reducing long-term survival after repair of acute type A dissection included age (P < .0001), new neurological deficit at presentation (P = .04), absence of preoperative thrombus in the false lumen of the ascending aorta (P = .03), and a patent distal false lumen postoperatively (P = .06) but not distal reoperation.

CONCLUSIONS:

Growth of the distal aorta after repair of acute type A dissection is typically slow and linear. Distal reoperation is uncommon, and late risk of death is approximately twice that of a healthy population.
Sujet(s)
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Collection: 01-internacional Base de données: MEDLINE Sujet principal: Aorte / Anévrysme de l&apos;aorte / Implantation de prothèses vasculaires / Type d'étude: Prognostic_studies / Risk_factors_studies Limites: Female / Humans / Male / Middle aged Langue: En Journal: J Thorac Cardiovasc Surg Année: 2007 Type de document: Article Pays d'affiliation: États-Unis d'Amérique
Recherche sur Google
Collection: 01-internacional Base de données: MEDLINE Sujet principal: Aorte / Anévrysme de l&apos;aorte / Implantation de prothèses vasculaires / Type d'étude: Prognostic_studies / Risk_factors_studies Limites: Female / Humans / Male / Middle aged Langue: En Journal: J Thorac Cardiovasc Surg Année: 2007 Type de document: Article Pays d'affiliation: États-Unis d'Amérique