Sequencing and comparative genomic analysis of pK29, a 269-kilobase conjugative plasmid encoding CMY-8 and CTX-M-3 beta-lactamases in Klebsiella pneumoniae.
Antimicrob Agents Chemother
; 51(8): 3004-7, 2007 Aug.
Article
de En
| MEDLINE
| ID: mdl-17526756
ABSTRACT
A 269-kilobase conjugative plasmid, pK29, from a Klebsiella pneumoniae strain was sequenced. The plasmid harbors multiple antimicrobial resistance genes, including those encoding CMY-8 AmpC-type and CTX-M-3 extended-spectrum beta-lactamases in the common backbone of IncHI2 plasmids. Mechanisms for dissemination of the resistance genes are highlighted in comparative genomic analyses.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Plasmides
/
Bêta-Lactamases
/
Analyse de séquence d'ADN
/
Conjugaison génétique
/
Génomique
/
Klebsiella pneumoniae
Limites:
Humans
Langue:
En
Journal:
Antimicrob Agents Chemother
Année:
2007
Type de document:
Article
Pays d'affiliation:
Taïwan