A case of new mutation in maturity-onset diabetes of the young type 3 (MODY 3) responsive to a low dose of sulphonylurea.
Diabetes Res Clin Pract
; 81(1): e1-3, 2008 Jul.
Article
de En
| MEDLINE
| ID: mdl-18433912
ABSTRACT
We describe a girl aged 10.5 years with hyperglycemia, whose mother and maternal father had insulin treated diabetes since adolescence. Using genetic analysis in mother and child, we identified identical new mutation of the HNF-1alpha sequence. Treatment with small doses of sulphonylurea was initiated and that therapy gave good results.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Sulfonylurées
/
Diabète de type 2
/
Facteur nucléaire hépatocytaire HNF-1 alpha
/
Hypoglycémiants
/
Mutation
Type d'étude:
Diagnostic_studies
/
Prognostic_studies
Limites:
Child
/
Female
/
Humans
/
Male
/
Pregnancy
Langue:
En
Journal:
Diabetes Res Clin Pract
Sujet du journal:
ENDOCRINOLOGIA
Année:
2008
Type de document:
Article