Isolation and culture of rodent osteoprogenitor cells.
Methods Mol Biol
; 455: 3-18, 2008.
Article
de En
| MEDLINE
| ID: mdl-18463807
ABSTRACT
Osteoblasts are the cells responsible for formation of new bone throughout life. Rats are one of the most widely studied mammalian species in skeletal biology and serve as useful models for many aspects of human skeletal physiology. The availability of genetically modified mice as research tools has greatly enabled our understanding of how specific genes contribute to the process of skeletogenesis. In order to explore the impact of biochemical, genetic, or pharmacological manipulation on bone formation, various osteogenic cell culture systems have been developed. Two of the most widely accepted rodent osteogenic culture models, using osteoprogenitor cells isolated from calvaria or bone marrow, are described in this chapter.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Ostéoblastes
/
Cellules souches
/
Techniques de culture cellulaire
Limites:
Animals
/
Humans
Langue:
En
Journal:
Methods Mol Biol
Sujet du journal:
BIOLOGIA MOLECULAR
Année:
2008
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique