Effect of Chinese herbal medicine combined with acitretin capsule in treating psoriasis of blood-heat syndrome type.
Chin J Integr Med
; 15(2): 141-4, 2009 Apr.
Article
de En
| MEDLINE
| ID: mdl-19407953
OBJECTIVE: To observe the clinical curative effect of Chinese herbal medicine combined with acitretin capsule in treating psoriasis of blood-heat syndrome (P-BH). METHODS: Eighty patients of P-BH were randomly assigned to two groups, 39 in Group A and 41 in Group B. Both was treated with Chinese herbal medicines for clearing heat, cooling blood and removing toxic substance, and acitretin capsule was given to Group A additionally, with 8 weeks as one therapeutic course. The clinical curative effect was compared between groups, and the change of psoriasis activity severe index (PASI) scores before and after treatment was observed. RESULTS: The total effective rate in Group A was 84.2% and that in Group B 68.2%, also showing significance between groups (P<0.01). PASI score lowered significantly after treatment in both groups, showing statistical significance (P<0.01), but no significant difference between groups. Little adverse reaction was found in Group B, while in Group A, the adverse reaction was of even milder degree, which could be alleviated by adjusting the herbal medicine and symptomatic treatment administration. CONCLUSIONS: The effect of Chinese herbal medicine combined with acitretin capsule was superior to Chinese herbal medicine alone in treating P-BH, but the adverse reaction of acitretin capsule could be alleviated by adjusting the herbs used. However, the result is waiting to be verified further by larger samples.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Psoriasis
/
Médicaments issus de plantes chinoises
/
Acitrétine
/
Hémopathies
Type d'étude:
Clinical_trials
/
Diagnostic_studies
Limites:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Langue:
En
Journal:
Chin J Integr Med
Sujet du journal:
TERAPIAS COMPLEMENTARES
Année:
2009
Type de document:
Article
Pays d'affiliation:
Chine
Pays de publication:
Chine