Evidence for intestinal chloride secretion.
Exp Physiol
; 95(4): 471-8, 2010 Apr.
Article
de En
| MEDLINE
| ID: mdl-20233891
ABSTRACT
Intestinal fluid secretion is pivotal in the creation of an ideal environment for effective enzymatic digestion, nutrient absorption and stool movement. Since fluid cannot be actively secreted into the gut, this process is dependent on an osmotic gradient, which is mainly created by chloride transport by the enterocyte. A pathological dysbalance between fluid secretion and absorption leads to obstruction or potentially fatal diarrhoea. This article reviews the widely accepted model of intestinal chloride secretion with an emphasis on the molecular players involved in this tightly regulated process.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Chlorures
/
Entérocytes
/
Muqueuse intestinale
/
Sécrétions intestinales
Limites:
Animals
/
Humans
Langue:
En
Journal:
Exp Physiol
Sujet du journal:
FISIOLOGIA
Année:
2010
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique