Contribution of intracranial vertebral artery asymmetry to vestibular neuropathy.
J Neurol Neurosurg Psychiatry
; 82(7): 823-5, 2011 Jul.
Article
de En
| MEDLINE
| ID: mdl-20587480
ABSTRACT
OBJECTIVES:
To test the hypothesis that vertebral artery hypoplasia (VAH) may affect the lateralisation of vestibular neuropathy (VN), probably through haemodynamic effect on the vestibular labyrinth.METHODS:
69 patients with unilateral VN were examined with a magnetic resonance angiographic (MRA) and caloric test. 50 healthy subjects served as controls. The diagnosis of intracranial VAH was based on MRA if <0.22 cm in VA diameter and a diameter asymmetry index >40%. The authors then correlated the canal paretic side with the VAH side.RESULTS:
MRA study revealed 29 VAH (right/left 23/6) in VN subjects and six VAH in controls (right/left 5/1). The RR of VAH in VN subjects compared with controls was elevated (RR=2.2; 95% CI 1.8 to 2.8). There was a high accordance rate between the side of VAH and VN. Among 29 patients with unilateral VAH, 65.5% (N=19) had an ipsilateral VN, in which left VAH showed a higher accordance rate (83.3%) than the right side (60.9%). VN subjects with vascular risk factors also had a higher VAH accordance rate (81%) than those without (25%).CONCLUSIONS:
VAH may serve as a regional haemodynamic negative contributor and impede blood supply to the ipsilateral vestibular labyrinth, contributing to the development of VN, which could be enhanced by atherosclerotic risk factors and the left-sided location.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Artère vertébrale
/
Névrite vestibulaire
Type d'étude:
Clinical_trials
/
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limites:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Langue:
En
Journal:
J Neurol Neurosurg Psychiatry
Année:
2011
Type de document:
Article
Pays d'affiliation:
Chine