Ectopic fat and cardiovascular disease: what is the link?
Nutr Metab Cardiovasc Dis
; 20(7): 481-90, 2010 Sep.
Article
de En
| MEDLINE
| ID: mdl-20659791
ABSTRACT
AIM:
of this paper is to review the recent literature on the relationship between ectopic fat accumulation and cardiovascular disease. DATASYNTHESIS:
Ectopic fat is an important predictor of metabolic (in particular insulin resistance) and cardiovascular disease, carrying more risk than general fat accumulation. Recent studies have shown a link between ectopic fat accumulation, as cardiac (epicardial or intra-myocardial fat) and/or visceral and/or hepatic fat, and development of atherosclerosis, coronary heart disease and hypertension.CONCLUSIONS:
Ectopic fat accumulation is not only a marker of cardiometabolic disease, since through the release of adipocitokines, lipotoxic and glucotoxic agents, participates in the crosstalk with insulin-sensitive organs leading to metabolic, cardiac and vascular dysfunctions.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Maladies cardiovasculaires
/
Tissu adipeux
/
Adiposité
/
Obésité
Type d'étude:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limites:
Animals
/
Humans
Langue:
En
Journal:
Nutr Metab Cardiovasc Dis
Sujet du journal:
ANGIOLOGIA
/
CARDIOLOGIA
/
CIENCIAS DA NUTRICAO
/
METABOLISMO
Année:
2010
Type de document:
Article
Pays d'affiliation:
Italie