Intrathecal synthesis of immunoglobulins in patients with unexplained intermediate uveitis.
Ocul Immunol Inflamm
; 19(1): 26-31, 2011 Feb.
Article
de En
| MEDLINE
| ID: mdl-20735295
ABSTRACT
PURPOSE:
To assess the value of lumbar punctures in adult patients with unexplained intermediate uveitis (IU).METHODS:
Retrospective study of 17 patients with unexplained IU. All the patients underwent physical examination, complete laboratory tests, and cerebrospinal MRI.RESULTS:
Out of the 12 patients who underwent a lumbar puncture, six had oligoclonal bands and/or increased IgG index.CONCLUSION:
Intrathecal synthesis of immunoglobulins is not rare in patients with unexplained IU. A longer follow-up is mandatory to determine whether intrathecal immunoglobulins synthesis has a predictive value for subsequent progression to multiple sclerosis.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Immunoglobulines
/
Uvéite intermédiaire
Type d'étude:
Observational_studies
/
Risk_factors_studies
Limites:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Langue:
En
Journal:
Ocul Immunol Inflamm
Sujet du journal:
ALERGIA E IMUNOLOGIA
/
OFTALMOLOGIA
Année:
2011
Type de document:
Article
Pays d'affiliation:
France