Assessment of left ventricular volumes, ejection fraction and mass. Comparison of model-based analysis of ECG-gated (99m)Tc-SPECT and ¹8F-FDG-PET.
Nuklearmedizin
; 50(1): 9-14, 2011.
Article
de En
| MEDLINE
| ID: mdl-21165540
ABSTRACT
AIM:
We compared and delineated possible differences of model-based analysis of ECG-gated SPECT using (99m)Tc-sestamibi (Tc-SPECT) with ECG-gated ¹8F-fluorodeoxyglucose-PET (FDG-PET) for determination of end-diastolic (EDV) and end-systolic (ESV) cardiac volumes, left ventricular ejection fraction (LVEF), and myocardial mass (LVMM). PATIENTS,METHODS:
24 patients (21 men; age 54±12years) with coronary artery disease underwent Tc-SPECT and FDG-PET imaging for evaluation of myocardial perfusion and viability. By using model-based analysis EDV, ESV, LVEF and LVMM were calculated from short axis images of both Tc-SPECT and FDG-PET.RESULTS:
Left ventricular volumes by Tc-SPECT and FDG-PET were 176±60 ml and 181±59 ml for EDV, and 97±44 ml and 103±45 ml for ESV respectively, LVEF was 47±8% by Tc-SPECT and 45±9% by FDG-PET. The LVMM was 214±40 g (Tc-SPECT) and 202±43 g (FDG-PET) (all p = NS, paired t-test). A significant correlation was observed between Tc-SPECT and FDG-PET imaging for calculation of EDV (r = 0.93), ESV (r = 0.93), LVEF (r = 0.83) and LVMM (r = 0.72).CONCLUSION:
ECG-gated Tc-SPECT and FDG-PET using two tracers with different characteristics (perfusion versus metabolism) showed close agreement concerning measurements of left ventricular volumes, contractile function and myocardial mass by using a model-based analysis.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Débit systolique
/
Technétium
/
Dysfonction ventriculaire gauche
/
Fluorodésoxyglucose F18
/
Techniques d'imagerie cardiaque synchronisée
Type d'étude:
Diagnostic_studies
/
Evaluation_studies
/
Prognostic_studies
Limites:
Female
/
Humans
/
Male
/
Middle aged
Langue:
En
Journal:
Nuklearmedizin
Année:
2011
Type de document:
Article
Pays d'affiliation:
Autriche