Mucosa-associated lymphoid tissue lymphoma of the third eyelid conjunctiva in a dog.
Vet Ophthalmol
; 14(1): 61-5, 2011 Jan.
Article
de En
| MEDLINE
| ID: mdl-21199281
ABSTRACT
A 4-year-old, neutered female Cocker Spaniel was presented to the veterinary clinic for protrusion of the left third eyelid. When the third eyelids from both eyes were everted, lobulated masses were present on the bulbar surface. The left third eyelid had a larger protrusion. There was no apparent associated ocular or systemic involvement. The tumor of left third eyelid was removed and referred for histological examination. Histologically, there were proliferations of lymphoid follicles surrounded by lymphoid cells forming a marginal zone. Those lymphoid cells occasionally infiltrated into conjunctival epithelium. A few apoptotic bodies with karyopyknotic and karyorrhexic nuclei were observed in the germinal center of lymphoid follicles. Mitotic figures were rare. On immunohistochemistry, tumor cells expressed CD79a but not CD3. A diagnosis of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) of the third eyelid was established based on the histological and immunophenotypical features. At the 1-year follow-up, there was no evidence of recurrence of the mass at the area of excision of the left third eyelid and the remaining tumor of the right third eyelid was still a similar size. The dog still showed no significant findings, except those of the tumor, and no evidence of systemic involvement. To the authors' knowledge, this is the first reported case of MALT lymphoma of the third eyelid in a dog.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Lymphome B de la zone marginale
/
Tumeurs de la conjonctive
/
Maladies des chiens
Type d'étude:
Diagnostic_studies
/
Risk_factors_studies
Limites:
Animals
Langue:
En
Journal:
Vet Ophthalmol
Sujet du journal:
MEDICINA VETERINARIA
/
OFTALMOLOGIA
Année:
2011
Type de document:
Article