In vivo imaging neurotransmitter function. The rat 6-hydroxydopamine model and its relevance for human Parkinson's disease.

Nikolaus, S; Larisch, R; Vosberg, H; Beu, M; Hautzel, H; Wirrwar, A; Mueller, H-W; Antke, C

Nikolaus, S; Larisch, R; Vosberg, H; Beu, M; Hautzel, H; Wirrwar, A; Mueller, H-W; Antke, C.

Affiliation

Nikolaus S; Clinic of Nuclear Medicine, University Hospital Düsseldorf, 40225 Düsseldorf, Germany. Susanne.Nikolaus@uni-duesseldorf.de

Nuklearmedizin ; 50(4): 155-66, 2011.

Article de En | MEDLINE | ID: mdl-21409317

ABSTRACT

ABSTRACT

This article gives an overview of those small animal imaging studies which have been conducted on neurotransmitter function in the rat 6-hydoxydopamine (6-OHDA) model of Parkinson's disease, and discusses findings with respect to the outcome of clinical studies on Parkinsonian patients.

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Encéphale / Oxidopamine / Agents neuromédiateurs / Syndromes parkinsoniens / Modèles animaux de maladie humaine / Imagerie moléculaire Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: Nuklearmedizin Année: 2011 Type de document: Article Pays d'affiliation: Allemagne

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