Efficacy of dioctahedral smectite in acute watery diarrhea in Indian children: a randomized clinical trial.
J Trop Pediatr
; 58(1): 63-7, 2012 Feb.
Article
de En
| MEDLINE
| ID: mdl-21525141
ABSTRACT
OBJECTIVE:
To determine the effects and safety of dioctahedral smectite (DS) on the duration of acute watery diarrhea in children.METHODS:
A Randomized, open labeled, clinical controlled trial in a tertiary care hospital outpatient department (OPD) and emergency department. Participants were one hundred and seventeen children without any chronic illness between 2 and 5 years presenting to OPD, having acute watery diarrhea for <48 h with mild to moderate dehydration, not on antibiotics and requiring oral rehydration therapy. Intervention done was DS with a dose of 1.5 g thrice daily.RESULTS:
Freshly dissolved DS in a dose of 1.5 g thrice daily for 5 days significantly shortened the duration of acute watery diarrhea in children aged 2-5 years. There were no adverse effects on the use of DS. DS was acceptable to the children, and its administration was not accompanied with any side effects.CONCLUSION:
DS reduces the duration of diarrhea in Indian children and prevents a prolonged course, and therefore, may consistently reduce the costs in treatment of acute watery diarrhea.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Solutions réhydratation
/
Silicates
/
Déshydratation
/
Diarrhée
Type d'étude:
Clinical_trials
Limites:
Child, preschool
/
Female
/
Humans
/
Male
Pays/Région comme sujet:
Asia
Langue:
En
Journal:
J Trop Pediatr
Année:
2012
Type de document:
Article
Pays d'affiliation:
Inde