Histological staining of amyloid and pre-amyloid peptides and proteins in mouse tissue.
Methods Mol Biol
; 849: 411-24, 2012.
Article
de En
| MEDLINE
| ID: mdl-22528106
ABSTRACT
The increased availability of transgenic mouse models for studying human diseases has shifted the focus of many laboratories from in vitro to in vivo assays. Herein, methods are described to allow investigators to obtain well-preserved mouse tissue to be stained with the standard histological dyes for amyloid, Congo Red, and Thioflavin S. These sections can as well be used for immunohistological procedures that allow detection of tissue amyloid and pre-amyloid, such as those composed of the amyloid-ß peptide, the tau protein, and the islet amyloid polypeptide.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Coloration et marquage
/
Peptides bêta-amyloïdes
/
Protéines tau
/
Polypeptide amyloïde des ilots
Limites:
Animals
/
Humans
Langue:
En
Journal:
Methods Mol Biol
Sujet du journal:
BIOLOGIA MOLECULAR
Année:
2012
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique