Lymphadenopathic Kaposi's sarcoma in an immunocompetent adult.
J Coll Physicians Surg Pak
; 22(6): 403-5, 2012 Jun.
Article
de En
| MEDLINE
| ID: mdl-22630105
ABSTRACT
Kaposi's sarcomas (KS) are vascular lesions which usually originate from multiple sites in the mid-dermis extending to the dermis. The aetiology is unknown, but infection from human herpes virus type 8 has been suggested. Several reports of KS had come from Africa initially and from worldwide later due to the close association with HIV/AIDS. Prior to this however, KS was very frequent in Eastern Europe, Italy and the United States where it existed in an indolent form in the elderly men of Jewish ancestry. KS may also be due to iatrogenic immune suppression from chronic use of steroids, elevated degree of expression of numerous cytokines and angiogenic growth factors including TNF alpha, IL-6, bFGF, HIVtat protein and oncostatin M. Lymphadenopathic KS involves the lymph-nodes, viscera and the gastrointestinal tract and may run a disseminated and aggressive course. We are reporting one such case in an immunocompetent male.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Sarcome de Kaposi
Type d'étude:
Diagnostic_studies
Limites:
Humans
/
Male
/
Middle aged
Langue:
En
Journal:
J Coll Physicians Surg Pak
Sujet du journal:
MEDICINA
Année:
2012
Type de document:
Article
Pays d'affiliation:
Nigeria