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How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology?
Biotechnol J ; 7(12): 1522-9, 2012 Dec.
Article de En | MEDLINE | ID: mdl-22949408
This report highlights the potential of measurement, monitoring, modeling and control (M(3) C) methodologies in animal and human cell culture technology. In particular, state-of-the-art of M(3) C technologies and their industrial relevance of existing technology are addressed. It is a summary of an expert panel discussion between biotechnologists and biochemical engineers with both academic and industrial backgrounds. The latest ascents in M(3) C are discussed from a cell culture perspective for industrial process development and production needs. The report concludes with a set of recommendations for targeting M(3) C research toward the industrial interests. These include issues of importance for biotherapeutics production, miniaturization of measurement techniques and modeling methods.
Sujet(s)

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Biotechnologie / Industrie pharmaceutique Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: Biotechnol J Sujet du journal: BIOTECNOLOGIA Année: 2012 Type de document: Article Pays d'affiliation: Portugal Pays de publication: Allemagne

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Biotechnologie / Industrie pharmaceutique Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: Biotechnol J Sujet du journal: BIOTECNOLOGIA Année: 2012 Type de document: Article Pays d'affiliation: Portugal Pays de publication: Allemagne