Enhanced detection of virus particles by nanoisland-based localized surface plasmon resonance.
Biosens Bioelectron
; 41: 249-55, 2013 Mar 15.
Article
de En
| MEDLINE
| ID: mdl-22959011
ABSTRACT
In this paper, we investigate localized surface plasmon resonance (SPR) detection based on nanoislands. Theoretical calculation performed with rigorous coupled-wave analysis and analytical transfer matrix method using effective medium theory suggests improvement on nanoislands in the limit of detection and sensitivity over conventional thin film-based SPR detection. Experimental results obtained with non-specific detection of ambient adenovirus confirm the improvement by more than one order of magnitude increase in the limit of detection. The enhancement achieved with nanoislands was explored in connection with efficient overlap between target and near-field distribution produced by nanoislands.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Virion
/
Techniques de biocapteur
/
Adenoviridae
/
Résonance plasmonique de surface
/
Nanotechnologie
/
Nanoparticules
Type d'étude:
Diagnostic_studies
Langue:
En
Journal:
Biosens Bioelectron
Sujet du journal:
BIOTECNOLOGIA
Année:
2013
Type de document:
Article