Multiple resonance fiber-optic sensor with time division multiplexing for multianalyte detection.
Opt Lett
; 37(19): 3969-71, 2012 Oct 01.
Article
de En
| MEDLINE
| ID: mdl-23027248
ABSTRACT
A proof-of-concept multiwindow fiber-optic sensor utilizing multiple particle plasmon resonance (PPR) of silver nanoparticles and gold nanorods separately on two unclad portions of the fiber for multianalyte detection is demonstrated. The detection is based on intensity interrogation of multiple wavelengths by a single detector. Time division multiplexing is employed to modulate the illumination of dual-wavelength LEDs to induce PPRs for simultaneous real-time and label-free monitoring of two types of biomolecular interactions. Preliminary results reveal that a refractive index resolution of 9 ×10(-6) RIU is achieved. Moreover, the measured intensities of two windows independently respond to their respective binding events. The potential of the sensor architecture with multiple sensing windows for cascaded, higher throughput, and multianalyte biochemical detection can be expected.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Résonance plasmonique de surface
/
Fibres optiques
Type d'étude:
Diagnostic_studies
Limites:
Animals
Langue:
En
Journal:
Opt Lett
Année:
2012
Type de document:
Article
Pays d'affiliation:
Taïwan