[Absorption disorders following gastric resection--morphological and enzyme-histochemical observations on the small intestinal mucosa].
Nihon Shokakibyo Gakkai Zasshi
; 87(1): 39-48, 1990 Jan.
Article
de Ja
| MEDLINE
| ID: mdl-2329730
ABSTRACT
For the purpose of studying digestion and absorption disorders following stomach surgery, particularly with respect to membrane digestive functional disorders, morphological and enzyme-histochemical observation of the small intestinal mucosa was performed, and a comparison was done between the partial gastrectomy group (59 cases), and the total gastrectomy group (52 cases). The following results were obtained 1) The small intestinal mucosa showed a tendency to significant villous atrophy in post-operative groups. 2) There was a significant decrease in the disaccharidase activity, especially in the small intestine of the total gastrectomy group. ALP, LAP and gamma-GPT activity also decreased, or disappeared in the small intestines showing villous atrophy. 3) In the atrophied mucosa which showed a marked decrease in membraneous enzyme activity, poorly-formed, irregularly sized microvilli accompanied by glycocalyx irregularity and disappearance were recognized under the electron microscope. The above mentioned morphological and enzyme-histological findings in the small intestinal mucosa, were strongly reflected in both post-operative progress and clinical symptoms.
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Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Syndromes post-gastrectomie
/
Gastrectomie
/
Muqueuse intestinale
/
Intestin grêle
/
Syndromes de malabsorption
Limites:
Female
/
Humans
/
Male
/
Middle aged
Langue:
Ja
Journal:
Nihon Shokakibyo Gakkai Zasshi
Année:
1990
Type de document:
Article