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[About a note published in 1926 on a BCG vaccine trial in leprosy treatment]. / À propos d'une note de 1926 sur un essai du BCG dans le traitement de la lèpre.
Chastel, C; Chastel, A.
Affiliation
  • Chastel C; 3, rue Rouget de l'Isle, 29200, Brest, France. chastelc@aol.com
Bull Soc Pathol Exot ; 106(2): 126-30, 2013 May.
Article de Fr | MEDLINE | ID: mdl-23456485
By 1926, two French physicians working in Indochina, R. Pons and L. Chastel, have suggested to treat leprosy by subcutaneous injections of bacillus Calmette-Guerin. This treatment appeared efficient since the lepromatous lesions quickly regressed and the Hansen bacillus disappeared from the nasal mucus. These results were quickly confirmed by other authors. They were all more appreciated than, at this time, the Chaulmoogra oil and its products, the only available drugs, were poorly efficient against the disease. Nevertheless, although not a panacea, the BCG therapy allowed to relieve these unfortunate patients until the beginning of the 1950's when an effective treatment by sulfones was at length available.
Sujet(s)

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Vaccin BCG / Lèpre lépromateuse / Immunothérapie active / Médecine militaire Limites: Humans Pays/Région comme sujet: Asia Langue: Fr Journal: Bull Soc Pathol Exot Année: 2013 Type de document: Article Pays d'affiliation: France Pays de publication: France

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Vaccin BCG / Lèpre lépromateuse / Immunothérapie active / Médecine militaire Limites: Humans Pays/Région comme sujet: Asia Langue: Fr Journal: Bull Soc Pathol Exot Année: 2013 Type de document: Article Pays d'affiliation: France Pays de publication: France