Metabolic syndrome and the risk for recurrent pre-eclampsia: a retrospective cohort study.
BJOG
; 120(8): 979-86, 2013 Jul.
Article
de En
| MEDLINE
| ID: mdl-23464593
ABSTRACT
OBJECTIVE:
To compare the prevalence of recurrent pre-eclampsia between women who have and do not have metabolic syndrome when non-pregnant.DESIGN:
Retrospective cohort study.SETTING:
Three tertiary referral hospitals in the Netherlands. POPULATION Formerly pre-eclamptic women.METHODS:
The presence or absence of metabolic syndrome was assessed in 480 women at least 6 months after their first pre-eclamptic pregnancy using World Health Organization criteria. We compared the prevalence of recurrent pre-eclampsia in the subsequent pregnancy, calculating odds ratios (OR), adjusted for confounders. MAIN OUTCOMEMEASURE:
Recurrence of pre-eclampsia in the subsequent pregnancy.RESULTS:
Subsequent pregnancy outcome data were available for 197 women. Forty women had metabolic syndrome after previous pregnancy (20%). The prevalence of recurrent pre-eclampsia was 18/40 (45%) in women with metabolic syndrome versus 27/157 (17%) in women without metabolic syndrome; OR 3.94 (95% confidence interval [CI] 1.86-8.33, adjusted OR 3.77 (95% CI 1.61-8.81). The risk of recurrent pre-eclampsia increased with each extra component of the metabolic syndrome from 11.8% for absent components up to 43.9% for three or more (P for trend < 0.001).CONCLUSIONS:
Interpregnancy metabolic syndrome predisposes to recurrent pre-eclampsia.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Pré-éclampsie
/
Syndrome métabolique X
Type d'étude:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limites:
Adult
/
Female
/
Humans
/
Pregnancy
Pays/Région comme sujet:
Europa
Langue:
En
Journal:
BJOG
Sujet du journal:
GINECOLOGIA
/
OBSTETRICIA
Année:
2013
Type de document:
Article
Pays d'affiliation:
Pays-Bas