The effect of seven vasopressors of halothane MAC in dogs.
Br J Anaesth
; 47(4): 435-8, 1975 Apr.
Article
de En
| MEDLINE
| ID: mdl-237518
ABSTRACT
We evaluated the effects of ephedrine, mephentermine, metaraminol, phenylephrine, methoxamine, noradrenaline and adrenaline on halothane anaesthetic requirement (MAC) in dogs. MAC increased significantly only during ephedrine infusion (50%) although significance was approached with mephentermine (21%). Phenylephrine, metaraminol, methoxamine, noradrenaline and adrenaline did not change MAC. Arterial pressure was increased 50-100% with all agents. Our results support the hypothesis that anaesthetic requirement may be related, in part, to release of brain noradrenaline.
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Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Vasoconstricteurs
/
Halothane
/
Anesthésie par inhalation
Limites:
Animals
Langue:
En
Journal:
Br J Anaesth
Année:
1975
Type de document:
Article