Deleted in breast cancer-1 (DBC-1) in the interface between metabolism, aging and cancer.
Biosci Rep
; 33(4)2013 Aug 23.
Article
de En
| MEDLINE
| ID: mdl-23841676
ABSTRACT
DBC1 (deleted in breast cancer-1) is a nuclear protein that regulates cellular metabolism. Since alteration in cellular metabolism have been proposed to be the emerging 'hallmark' of cancer, it is possible that DBC1 may be implicated in the regulation of cancer cell energy metabolism. However, at this point any role of DBC1 in cancer is only speculative. In this review, we will discuss the new developments in DBC1 research, its molecular structure, regulatory roles and implication in metabolism, aging and cancer.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Vieillissement
/
Protéines adaptatrices de la transduction du signal
/
Métabolisme énergétique
/
Tumeurs
Limites:
Animals
/
Humans
Langue:
En
Journal:
Biosci Rep
Année:
2013
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique