Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma.

Ene-Obong, Abasi; Clear, Andrew J; Watt, Jennifer; Wang, Jun; Fatah, Rewas; Riches, John C; Marshall, John F; Chin-Aleong, Joanne; Chelala, Claude; Gribben, John G; Ramsay, Alan G; Kocher, Hemant M

Ene-Obong, Abasi; Clear, Andrew J; Watt, Jennifer; Wang, Jun; Fatah, Rewas; Riches, John C; Marshall, John F; Chin-Aleong, Joanne; Chelala, Claude; Gribben, John G; Ramsay, Alan G; Kocher, Hemant M.

Affiliation

Ene-Obong A; Centre for Tumour Biology, Barts Cancer Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, England.

Gastroenterology ; 145(5): 1121-32, 2013 Nov.

Article de En | MEDLINE | ID: mdl-23891972

Sujet(s)
Mots clés

AC; ATRA; Antitumor Immunity; CC; Immune Regulation; MDSC; Mouse Model; PBD; PDAC; PSC; Pancreatic Cancer; TMA; Treg; aPSC; activated pancreatic stellate cell; all-trans retinoic acid; ampullary carcinoma; cholangiocarcinoma; myeloid-derived suppressor cell; pancreatic ductal adenocarcinoma; pancreatic stellate cell; pancreaticobiliary disease; qPSC; quiescent pancreatic stellate cell; regulatory T cell; tissue microarray

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs du pancréas / Adénocarcinome / Mouvement cellulaire / Lymphocytes T CD8/ / Carcinome du canal pancréatique / Cellules stellaires pancréatiques Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: Gastroenterology Année: 2013 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: États-Unis d'Amérique

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