Quality of life in immune thrombocytopenia following treatment.
Arch Dis Child
; 98(11): 895-7, 2013 Nov.
Article
de En
| MEDLINE
| ID: mdl-23956257
ABSTRACT
OBJECTIVE:
To determine the impact of therapy on the reported health-related quality of life (HRQoL) in children with primary immune thrombocytopenia (ITP) using the Kids ITP tool (KIT).DESIGN:
Secondary data analysis of the international and North American KIT validation studies.RESULTS:
217 children from 6 countries participated in the two studies. The majority of treatments occurred in children with newly diagnosed ITP. There was no statistical difference in age, platelet count and bleeding severity at presentation in those who physicians chose to treat or observe. Self-reported KIT scores did not differ between the two groups. The KIT parent-proxy scores were significantly worse for newly diagnosed children receiving treatment, especially following prednisone.CONCLUSIONS:
Treatment of ITP does not improve, and may worsen, the HRQoL of children with ITP as measured using the KIT.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Qualité de vie
/
Purpura thrombopénique idiopathique
Type d'étude:
Clinical_trials
Aspects:
Patient_preference
Limites:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Langue:
En
Journal:
Arch Dis Child
Année:
2013
Type de document:
Article
Pays d'affiliation:
Royaume-Uni