PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex.

Vu, Ly P; Perna, Fabiana; Wang, Lan; Voza, Francesca; Figueroa, Maria E; Tempst, Paul; Erdjument-Bromage, Hediye; Gao, Rui; Chen, Sisi; Paietta, Elisabeth; Deblasio, Tony; Melnick, Ari; Liu, Yan; Zhao, Xinyang; Nimer, Stephen D

Vu, Ly P; Perna, Fabiana; Wang, Lan; Voza, Francesca; Figueroa, Maria E; Tempst, Paul; Erdjument-Bromage, Hediye; Gao, Rui; Chen, Sisi; Paietta, Elisabeth; Deblasio, Tony; Melnick, Ari; Liu, Yan; Zhao, Xinyang; Nimer, Stephen D.

Affiliation

Vu LP; Molecular Pharmacology and Chemistry Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Gerstner Sloan-Kettering Graduate School of Biomedical Sciences, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Perna F; Molecular Pharmacology and Chemistry Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Wang L; Molecular Pharmacology and Chemistry Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Department of Biochemistry and Molecular Biology, Sylvester Comprehensive Cancer Center, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
Voza F; Molecular Pharmacology and Chemistry Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Figueroa ME; Department of Pathology, the University of Michigan Medical School, Ann Arbor, MI, 48109, USA.
Tempst P; Molecular Biology Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Erdjument-Bromage H; Molecular Biology Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Gao R; Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Chen S; Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Paietta E; Cancer Center, Montefiore Medical Center-North Division, Bronx, NY 10466, USA.
Deblasio T; Molecular Pharmacology and Chemistry Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Melnick A; Department of Medicine, Hematology Oncology Division, Weill Cornell Medical College, New York, NY 10065, USA.
Liu Y; Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Zhao X; Molecular Pharmacology and Chemistry Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Department of Biochemistry & Molecular Genetics, University of Alabama, Birmingham, AL 35294, USA. Electronic address: zhaox88@uab.edu.
Nimer SD; Molecular Pharmacology and Chemistry Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Gerstner Sloan-Kettering Graduate School of Biomedical Sciences, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Department of Biochemistry and M

Cell Rep ; 5(6): 1625-38, 2013 Dec 26.

Article de En | MEDLINE | ID: mdl-24332853

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Protein-arginine N-methyltransferases / Progéniteurs myéloïdes / Sous-unité alpha 2 du facteur CBF / Répression épigénétique / Hématopoïèse Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: Cell Rep Année: 2013 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique

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