Your browser doesn't support javascript.
loading
Optimization of a Potent, Orally Active S1P1 Agonist Containing a Quinolinone Core.
Harrington, Paul E; Croghan, Michael D; Fotsch, Christopher; Frohn, Mike; Lanman, Brian A; Pennington, Lewis D; Pickrell, Alexander J; Reed, Anthony B; Sham, Kelvin K C; Tasker, Andrew; Arnett, Heather A; Fiorino, Michael; Lee, Matthew R; McElvain, Michele; Morrison, Henry G; Xu, Han; Xu, Yang; Zhang, Xuxia; Wong, Min; Cee, Victor J.
Affiliation
  • Harrington PE; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
  • Croghan MD; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
  • Fotsch C; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
  • Frohn M; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
  • Lanman BA; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
  • Pennington LD; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
  • Pickrell AJ; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
  • Reed AB; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
  • Sham KK; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
  • Tasker A; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
  • Arnett HA; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
  • Fiorino M; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
  • Lee MR; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
  • McElvain M; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
  • Morrison HG; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
  • Xu H; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
  • Xu Y; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
  • Zhang X; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
  • Wong M; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
  • Cee VJ; Chemistry Research and Discovery, Inflammation Research, Molecular Structure, HTS and Molecular Pharmacology, Pharmaceutics, and Pharmacokinetics and Drug Metabolism, Amgen , One Amgen Center Drive, Thousand Oaks, California 91320-1799, United States.
ACS Med Chem Lett ; 3(1): 74-8, 2012 Jan 12.
Article de En | MEDLINE | ID: mdl-24900374
Mots clés
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: ACS Med Chem Lett Année: 2012 Type de document: Article Pays d'affiliation: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Langue: En Journal: ACS Med Chem Lett Année: 2012 Type de document: Article Pays d'affiliation: États-Unis d'Amérique