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Pharmacogenetics of warfarin in a paediatric population: time in therapeutic range, initial and stable dosing and adverse effects.
Hawcutt, D B; Ghani, A A; Sutton, L; Jorgensen, A; Zhang, E; Murray, M; Michael, H; Peart, I; Smyth, R L; Pirmohamed, M.
Affiliation
  • Hawcutt DB; 1] Institute of Translational Medicine, University of Liverpool, Liverpool, UK [2] Department of Research, Alder Hey Children's NHS Foundation Trust, Liverpool, UK.
  • Ghani AA; Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
  • Sutton L; Department of Biostatistics, University of Liverpool, Liverpool, UK.
  • Jorgensen A; Department of Biostatistics, University of Liverpool, Liverpool, UK.
  • Zhang E; Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
  • Murray M; Department of Cardiology, Alder Hey Children's NHS Foundation Trust, Liverpool, UK.
  • Michael H; Department of Cardiology, Alder Hey Children's NHS Foundation Trust, Liverpool, UK.
  • Peart I; Department of Cardiology, Alder Hey Children's NHS Foundation Trust, Liverpool, UK.
  • Smyth RL; Institute of Child Health, University College London (UCL), London, UK.
  • Pirmohamed M; Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
Pharmacogenomics J ; 14(6): 542-8, 2014 Dec.
Article de En | MEDLINE | ID: mdl-25001883

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Warfarine / Polymorphisme de nucléotide simple / Vitamin K epoxide reductases / Cytochrome P-450 CYP2C9 Type d'étude: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limites: Adolescent / Child / Child, preschool / Humans / Infant Langue: En Journal: Pharmacogenomics J Sujet du journal: BIOLOGIA MOLECULAR / FARMACOLOGIA Année: 2014 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: États-Unis d'Amérique

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Warfarine / Polymorphisme de nucléotide simple / Vitamin K epoxide reductases / Cytochrome P-450 CYP2C9 Type d'étude: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limites: Adolescent / Child / Child, preschool / Humans / Infant Langue: En Journal: Pharmacogenomics J Sujet du journal: BIOLOGIA MOLECULAR / FARMACOLOGIA Année: 2014 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: États-Unis d'Amérique