HMGCR is a genetic modifier for risk, age of onset and MCI conversion to Alzheimer's disease in a three cohorts study.

Leduc, V; De Beaumont, L; Théroux, L; Dea, D; Aisen, P; Petersen, R C; Dufour, R; Poirier, J

Leduc, V; De Beaumont, L; Théroux, L; Dea, D; Aisen, P; Petersen, R C; Dufour, R; Poirier, J.

Affiliation

Leduc V; 1] Centre for the Studies in the Prevention of Alzheimer's disease, Douglas Mental Health University Institute, Montreal, QC, Canada [2] Department of Nutrition, Institut de recherches cliniques de Montréal, Université de Montréal, Montreal, QC, Canada.
De Beaumont L; Centre for the Studies in the Prevention of Alzheimer's disease, Douglas Mental Health University Institute, Montreal, QC, Canada.
Théroux L; Centre for the Studies in the Prevention of Alzheimer's disease, Douglas Mental Health University Institute, Montreal, QC, Canada.
Dea D; Centre for the Studies in the Prevention of Alzheimer's disease, Douglas Mental Health University Institute, Montreal, QC, Canada.
Aisen P; Department of Neurosciences, University of California-San Diego, La Jolla, CA, USA.
Petersen RC; Alzheimer's Disease Research Center, Mayo Clinic College of Medicine, Rochester, MN, USA.
Dufour R; Department of Nutrition, Institut de recherches cliniques de Montréal, Université de Montréal, Montreal, QC, Canada.
Poirier J; 1] Centre for the Studies in the Prevention of Alzheimer's disease, Douglas Mental Health University Institute, Montreal, QC, Canada [2] Derparment of Psychiatry, McGill University, Verdun, QC, Canada.

Mol Psychiatry ; 20(7): 867-73, 2015 Jul.

Article de En | MEDLINE | ID: mdl-25023145

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Prédisposition génétique à une maladie / Polymorphisme de nucléotide simple / Maladie d'Alzheimer / Dysfonctionnement cognitif / Hydroxymethylglutaryl-CoA reductases Type d'étude: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limites: Aged / Aged80 / Female / Humans / Male / Middle aged Langue: En Journal: Mol Psychiatry Sujet du journal: BIOLOGIA MOLECULAR / PSIQUIATRIA Année: 2015 Type de document: Article Pays d'affiliation: Canada

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