Caveolin-1 is required for TGF-ß-induced transactivation of the EGF receptor pathway in hepatocytes through the activation of the metalloprotease TACE/ADAM17.

Moreno-Càceres, J; Caja, L; Mainez, J; Mayoral, R; Martín-Sanz, P; Moreno-Vicente, R; Del Pozo, M Á; Dooley, S; Egea, G; Fabregat, I

Moreno-Càceres, J; Caja, L; Mainez, J; Mayoral, R; Martín-Sanz, P; Moreno-Vicente, R; Del Pozo, M Á; Dooley, S; Egea, G; Fabregat, I.

Affiliation

Moreno-Càceres J; Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.
Caja L; Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.
Mainez J; Department of Cell Biology, Immunology and Neuroscience, School of Medicine IDIBAPS-University of Barcelona, Barcelona, Spain.
Mayoral R; 1] Department of Medicine, University of California, San Diego, La Jolla, CA, USA [2] Networked Biomedical Research Center on Hepatic and Digestive Diseases (CIBERehd), Madrid, Spain.
Martín-Sanz P; 1] Networked Biomedical Research Center on Hepatic and Digestive Diseases (CIBERehd), Madrid, Spain [2] Alberto Sols Biomedical Research Institute, CSIC-UAM, Madrid, Spain.
Moreno-Vicente R; Integrin Signaling Laboratory, National Center for Cardiovascular Research (CNIC), Madrid, Spain.
Del Pozo MÁ; Integrin Signaling Laboratory, National Center for Cardiovascular Research (CNIC), Madrid, Spain.
Dooley S; Molecular Hepatology section, Department of Medicine II, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Egea G; Department of Cell Biology, Immunology and Neuroscience, School of Medicine IDIBAPS-University of Barcelona, Barcelona, Spain.
Fabregat I; 1] Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain [2] Department of Physiological Sciences II, University of Barcelona, Barcelona, Spain.

Cell Death Dis ; 5: e1326, 2014 Jul 17.

Article de En | MEDLINE | ID: mdl-25032849

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Activation de la transcription / Facteur de croissance transformant bêta / Hépatocytes / Protéines ADAM / Cavéoline-1 / Récepteurs ErbB Limites: Animals Langue: En Journal: Cell Death Dis Année: 2014 Type de document: Article Pays d'affiliation: Espagne Pays de publication: Royaume-Uni

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