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Timosaponin A3 induces hepatotoxicity in rats through inducing oxidative stress and down-regulating bile acid transporters.
Wu, Zhi-tao; Qi, Xin-ming; Sheng, Jing-jing; Ma, Lei-lei; Ni, Xuan; Ren, Jin; Huang, Cheng-gang; Pan, Guo-yu.
Affiliation
  • Wu ZT; Center for Drug Safety Evaluation and Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Qi XM; Center for Drug Safety Evaluation and Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Sheng JJ; Nanjing Normal University, Nanjing 210000, China.
  • Ma LL; Center for Drug Safety Evaluation and Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Ni X; Center for Drug Safety Evaluation and Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Ren J; Center for Drug Safety Evaluation and Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Huang CG; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Pan GY; Center for Drug Safety Evaluation and Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Acta Pharmacol Sin ; 35(9): 1188-98, 2014 Sep.
Article de En | MEDLINE | ID: mdl-25087997
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Saponines / Stéroïdes / Acides et sels biliaires / Glycoprotéines membranaires / Protéines de transport / Régulation négative / Stress oxydatif / Hépatocytes / Foie Limites: Animals Langue: En Journal: Acta Pharmacol Sin Sujet du journal: FARMACOLOGIA Année: 2014 Type de document: Article Pays d'affiliation: Chine Pays de publication: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Saponines / Stéroïdes / Acides et sels biliaires / Glycoprotéines membranaires / Protéines de transport / Régulation négative / Stress oxydatif / Hépatocytes / Foie Limites: Animals Langue: En Journal: Acta Pharmacol Sin Sujet du journal: FARMACOLOGIA Année: 2014 Type de document: Article Pays d'affiliation: Chine Pays de publication: États-Unis d'Amérique