Negative regulation of signal transducer and activator of transcription-3 signalling cascade by lupeol inhibits growth and induces apoptosis in hepatocellular carcinoma cells.

Siveen, K S; Nguyen, A H; Lee, J H; Li, F; Singh, S S; Kumar, A P; Low, G; Jha, S; Tergaonkar, V; Ahn, K S; Sethi, G

Siveen, K S; Nguyen, A H; Lee, J H; Li, F; Singh, S S; Kumar, A P; Low, G; Jha, S; Tergaonkar, V; Ahn, K S; Sethi, G.

Affiliation

Siveen KS; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Nguyen AH; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Lee JH; Department of Pathology, College of Korean Medicine, Kyung Hee University, Seoul 130-701, Republic of Korea.
Li F; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Singh SS; 1] Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore [2] Cancer Science Institute of Singapore, Centre for Translational Medicine, 14 Medical Drive, Singapore 117599, Singapore.
Kumar AP; 1] Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore [2] Cancer Science Institute of Singapore, Centre for Translational Medicine, 14 Medical Drive, Singapore 117599, Singapore [3] Biomedical Sciences, Faculty of Health Science
Low G; 1] Cancer Science Institute of Singapore, Centre for Translational Medicine, 14 Medical Drive, Singapore 117599, Singapore [2] Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Jha S; 1] Cancer Science Institute of Singapore, Centre for Translational Medicine, 14 Medical Drive, Singapore 117599, Singapore [2] Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Tergaonkar V; Institute of Molecular and Cell Biology, A*STAR, Biopolis Drive Proteos, Singapore, Singapore.
Ahn KS; Department of Pathology, College of Korean Medicine, Kyung Hee University, Seoul 130-701, Republic of Korea.
Sethi G; 1] Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore [2] Cancer Science Institute of Singapore, Centre for Translational Medicine, 14 Medical Drive, Singapore 117599, Singapore.

Br J Cancer ; 111(7): 1327-37, 2014 Sep 23.

Article de En | MEDLINE | ID: mdl-25101566

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Transduction du signal / Apoptose / Facteur de transcription STAT-3 / Triterpènes pentacycliques / Antinéoplasiques Limites: Humans Langue: En Journal: Br J Cancer Année: 2014 Type de document: Article Pays d'affiliation: Singapour Pays de publication: Royaume-Uni

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