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Nonstructural protein 5A (NS5A) and human replication protein A increase the processivity of hepatitis C virus NS5B polymerase activity in vitro.
Mani, Nagraj; Yuzhakov, Alexander; Yuzhakov, Olga; Coll, Joyce T; Black, Jim; Saxena, Kumkum; Fulghum, John R; Lippke, Judith A; Rao, B Govinda; Rijnbrand, Rene; Kwong, Ann D.
Affiliation
  • Mani N; Infectious Diseases Department, Vertex Pharmaceuticals Incorporated, Boston, Massachusetts, USA nagraj_mani@yahoo.com.
  • Yuzhakov A; Infectious Diseases Department, Vertex Pharmaceuticals Incorporated, Boston, Massachusetts, USA.
  • Yuzhakov O; Infectious Diseases Department, Vertex Pharmaceuticals Incorporated, Boston, Massachusetts, USA.
  • Coll JT; Protein Sciences Department, Vertex Pharmaceuticals Incorporated, Boston, Massachusetts, USA.
  • Black J; Protein Sciences Department, Vertex Pharmaceuticals Incorporated, Boston, Massachusetts, USA.
  • Saxena K; Protein Sciences Department, Vertex Pharmaceuticals Incorporated, Boston, Massachusetts, USA.
  • Fulghum JR; Protein Sciences Department, Vertex Pharmaceuticals Incorporated, Boston, Massachusetts, USA.
  • Lippke JA; Protein Sciences Department, Vertex Pharmaceuticals Incorporated, Boston, Massachusetts, USA.
  • Rao BG; Computational Sciences Department, Vertex Pharmaceuticals Incorporated, Boston, Massachusetts, USA.
  • Rijnbrand R; Infectious Diseases Department, Vertex Pharmaceuticals Incorporated, Boston, Massachusetts, USA.
  • Kwong AD; Infectious Diseases Department, Vertex Pharmaceuticals Incorporated, Boston, Massachusetts, USA.
J Virol ; 89(1): 165-80, 2015 Jan.
Article de En | MEDLINE | ID: mdl-25320291
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Réplication virale / Protéines virales non structurales / Hepacivirus / Protéine A de réplication / Interactions hôte-pathogène Limites: Humans Langue: En Journal: J Virol Année: 2015 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Réplication virale / Protéines virales non structurales / Hepacivirus / Protéine A de réplication / Interactions hôte-pathogène Limites: Humans Langue: En Journal: J Virol Année: 2015 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique