Your browser doesn't support javascript.
loading
Reasons for cannabis use in first-episode psychosis: does strength of endorsement change over 12 months?
Kolliakou, A; Castle, D; Sallis, H; Joseph, C; O'Connor, J; Wiffen, B; Gayer-Anderson, C; McQueen, G; Taylor, H; Bonaccorso, S; Gaughran, F; Smith, S; Greenwood, K; Murray, R M; Di Forti, M; Atakan, Z; Ismail, K.
Affiliation
  • Kolliakou A; Department of Psychological Medicine, PO92, Institute of Psychiatry, King's College London, De Crespigny Park, SE5 8AF London, UK. Electronic address: anna.kolliakou@kcl.ac.uk.
  • Castle D; Department of Psychiatry, University of Melbourne, Melbourne, Australia.
  • Sallis H; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.
  • Joseph C; Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK.
  • O'Connor J; Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK.
  • Wiffen B; Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK.
  • Gayer-Anderson C; Department of Health Service and Population Research, Institute of Psychiatry, King's College London, London, UK.
  • McQueen G; Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK.
  • Taylor H; Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK.
  • Bonaccorso S; Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK.
  • Gaughran F; Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK.
  • Smith S; Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King's College London, London, UK.
  • Greenwood K; School of Psychology, University of Sussex, Sussex, UK.
  • Murray RM; Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK.
  • Di Forti M; Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK.
  • Atakan Z; Department of Neuroimaging, Institute of Psychiatry, King's College London, London, UK.
  • Ismail K; Department of Psychological Medicine, PO92, Institute of Psychiatry, King's College London, De Crespigny Park, SE5 8AF London, UK.
Eur Psychiatry ; 30(1): 152-9, 2015 Jan.
Article de En | MEDLINE | ID: mdl-25541346
ABSTRACT

BACKGROUND:

Why patients with psychosis use cannabis remains debated. The self-medication hypothesis has received some support but other evidence points towards an alleviation of dysphoria model. This study investigated the reasons for cannabis use in first-episode psychosis (FEP) and whether strength in their endorsement changed over time.

METHODS:

FEP inpatients and outpatients at the South London and Maudsley, Oxleas and Sussex NHS Trusts UK, who used cannabis, rated their motives at baseline (n=69), 3 months (n=29) and 12 months (n=36). A random intercept model was used to test the change in strength of endorsement over the 12 months. Paired-sample t-tests assessed the differences in mean scores between the five subscales on the Reasons for Use Scale (enhancement, social motive, coping with unpleasant affect, conformity and acceptance and relief of positive symptoms and side effects), at each time-point.

RESULTS:

Time had a significant effect on scores when controlling for reason; average scores on each subscale were higher at baseline than at 3 months and 12 months. At each time-point, patients endorsed 'enhancement' followed by 'coping with unpleasant affect' and 'social motive' more highly for their cannabis use than any other reason. 'Conformity and acceptance' followed closely. 'Relief of positive symptoms and side effects' was the least endorsed motive.

CONCLUSIONS:

Patients endorsed their reasons for use at 3 months and 12 months less strongly than at baseline. Little support for the self-medication or alleviation of dysphoria models was found. Rather, patients rated 'enhancement' most highly for their cannabis use.
Sujet(s)
Mots clés

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Troubles psychotiques / Fumer de la marijuana / Abus de marijuana Type d'étude: Prognostic_studies Limites: Adult / Aged / Female / Humans / Male / Middle aged Pays/Région comme sujet: Europa Langue: En Journal: Eur Psychiatry Sujet du journal: PSIQUIATRIA Année: 2015 Type de document: Article

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Troubles psychotiques / Fumer de la marijuana / Abus de marijuana Type d'étude: Prognostic_studies Limites: Adult / Aged / Female / Humans / Male / Middle aged Pays/Région comme sujet: Europa Langue: En Journal: Eur Psychiatry Sujet du journal: PSIQUIATRIA Année: 2015 Type de document: Article