A validated UPLC-MS/MS assay using negative ionization mode for high-throughput determination of pomalidomide in rat plasma.

Iqbal, Muzaffar; Ezzeldin, Essam; Al-Rashood, Khalid A; Shakeel, Faiyaz

Iqbal, Muzaffar; Ezzeldin, Essam; Al-Rashood, Khalid A; Shakeel, Faiyaz.

Affiliation

Iqbal M; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia; Bioavailability Laboratory, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia. Electronic address: muziqbal@gmail.com.
Ezzeldin E; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia; Bioavailability Laboratory, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Al-Rashood KA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Shakeel F; Department of Pharmaceutics, College of Pharmacy, King Saud University, P. O. Box 2457, Riyadh 11451, Saudi Arabia.

J Chromatogr B Analyt Technol Biomed Life Sci ; 983-984: 76-82, 2015 Mar 01.

Article de En | MEDLINE | ID: mdl-25621435

Sujet(s)
Mots clés

Pharmacokinetics; Pomalidomide; Rat plasma; UPLCMS/MS

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Thalidomide / Chromatographie en phase liquide à haute performance / Spectrométrie de masse en tandem / Tests de criblage à haut débit Limites: Animals Langue: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Sujet du journal: ENGENHARIA BIOMEDICA Année: 2015 Type de document: Article Pays de publication: Pays-Bas

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